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BIOMED Faculty Details: Simon Giszter, Ph.D.
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Simon Giszter, Ph.D.   [Update My Profile]
Associate Professor, Department of Neurobiology, Drexel University College of Medicine
Research Associate Professor, School of Biomedical Engineering, Science & Health Systems
Office: Drexel College of Medicine  Email: sgiszter@drexelmed.edu
Phone: 215.991.8412   Fax: 215.843.9082
Personal Web Page: Click Here to Visit Personal Web Page
Research Keywords:
Neuroscience, neuroengineering, computational neuroscience and motor control, neuro-biomechanical modularity, intraspinal and intracortical neuroprostheses, biomimetic and neuromimetic robot design and control.
Education:
BA Cambridge University 1978
PhD University of Oregon 1984
Postdocs UCLA 1985, and MIT 1986-1990
Active Research Projects:
Funding:
NIH R01 NS54894, NIH R01 NS76251, NSF CRCNS IIS 0827684

Project Areas:
Spinal cord organization:
Frog spinal cord and reflex organization as a set of motor primitives
Participants: Corey Hart, Tanuj Gulati, TaeGyo Kim, Arun Ramakrishnan and Simon Giszter

Rat motor primitives in locomotor adaptation, spinal cord injury and functional recovery
Participants: Ubong Ime Udoekwere, Fuhan Hsieh, Chintan Oza, Simon Giszter

Neurorobotic interfaces with Motor Cortex for locomotor Brain Machine Interfaces in adaptation
Participants: Chintan Oza, Kiki Yang, and Simon Giszter

Novel braided electrodes and uncaging methods of deep brain stimulation and FNS
Participants: TaeGyo Kim, Almut Branner and Simon Giszter
Colleagues and Collaborators: Michel Lemay, Dinesh Pai, Kiisa Nishikawa, Veronica Tom, Yinghui Zhong, Karen Moxon
Publications:
Selected:
Song W, Giszter SF.Adaptation to a cortex-controlled robot attached at the pelvis and engaged during locomotion in rats.J Neurosci. 2011 Feb 23;31(8):3110-28.

Giszter SF, Hockensmith G, Ramakrishnan A, Udoekwere UI. How spinalized rats can walk: biomechanics, cortex, and hindlimb muscle scaling--implications for rehabilitation. Ann N Y Acad Sci. 2010 Jun;1198:279-93.

Hart CB, Giszter SF.A neural basis for motor primitives in the spinal cord.J Neurosci. 2010 Jan 27;30(4):1322-36.

Kargo WJ, Ramakrishnan A, Hart CB, Rome LC, Giszter SF.A simple experimentally based model using proprioceptive regulation of motor primitives captures adjusted trajectory formation in spinal frogs.J Neurophysiol. 2010 Jan;103(1):573-90. Epub 2009 Aug 5.

Song W, Ramakrishnan A, Udoekwere UI, Giszter SF.Multiple types of movement-related information encoded in hindlimb/trunk cortex in rats and potentially available for brain-machine interface controls. IEEE Trans Biomed Eng. 2009 Nov;56(11 Pt 2):2712-6. Epub 2009 Jul 14.

Kargo WJ and Giszter SF (2008) Individual premotor drive pulses, not time-varying synergies, are the units of adjustment for limb trajectories constructed in spinal-cord. J. Neuroscience 5;28(10):2409-25.

Giszter SF Davies MR and Graziani V (2008) Coordination strategies for limb forces during weight-bearing locomotion in normal rats, and in rats spinalized as neonates. Exp. Brain Research. 190(1):53-69.

Giszter SF (2008) Spinal Cord Injury: Present and Future Therapeutic Devices and Prostheses. Neurotherapeutics 5(1):147-162.

Giszter SF, Davies MR, Ramakrishnan A, Udoekwere UI, Kargo WJ. (2008) Trunk sensorimotor cortex is essential for hindlimb weight-supported locomotion in adult rats spinalized as P1/P2 neonates. J. Neurophysiology 100(2):839-51.

Giszter SF Patil V and Hart CB (2007) Primitives, Premotor Drives and Pattern Generation: a combined Computational and Neuroethological Perspective. Prog. Brain Res. 165:325-349

Giszter SF Davies MR Graziani VG (2007) Motor strategies used by rats spinalized at birth to maintain stance in response to imposed perturbations. J. Neurophysiol. 97(4):2663-75.

ALSO
(see- http://www.ncbi.nlm.nih.gov/pubmed?term=giszter)
Patents:
Braided multielectrodes (2 pending)
Braid plate design (pending)
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