"Biologically Active Nanofibers – Paralyzed Limbs Move Again"

Samuel Stupp and collaborators at Northwestern University have designed a material that self-assembles into tiny tubes—nanofibers—when it comes in contact with tissues. The nanofibers are studded with short strings of amino acids that signal nerve cells to grow new extensions after spinal cord injury. Within weeks of receiving the bioactive nanofiber injection, mice paralyzed from spinal cord injury showed signs of recovery. By changing the bioactive molecules on the nanofibers, it will be possible to instruct cells to behave in a desired way. This work confirms that bioactive nanofiber technology holds promise for treating a broad range of injuries and diseases.

For the full story, please go to:
http://www.nibib.nih.gov/HealthEdu/eAdvances/26Nov08


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