Seminar - Regulation of Stem and Progenitor Cells Using Physical Cues
Date: November 9, 2007
Time: 4:00 PM
Location: Matheson Hall, Room: 109
Taby Ahsan, Ph.D.
Institute for Bioengineering & Bioscience
Georgia Institute of Technology
Controlling the physical microenvironment can serve to influence stem cell fate and/or facilitate regenerative medicine applications. Using a combination of bioreactors and biomaterials, one can study the role of physical cues in stem cell self-renewal and differentiation. Understanding these mechanisms is valuable in directed differentiation and design of cell culture bioprocessing for cell-based therapies. Our work has focused on vascular tissue engineering. Using three dimensional culture configurations and applied physical forces, such as shear stress and equibiaxial strain, we have shown that embryonic and mesenchymal stem cells can be differentiated towards endothelial and smooth muscle phenotypes.
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Taby Ahsan received a B.S.E in Bioengineering from the University of Pennsylvania and a Ph.D. in Bioengineering from the University of California, San Diego. For three years, Dr. Ahsan was in the tissue engineering industry at Advanced Tissue Sciences, Inc., working on orthopaedic tissue engineering and bioreactor design. Dr. Ahsan then returned to academics and was a Ruth L. Kirschstein NRSA fellow in the laboratory of Dr. Robert Nerem. Currently, Dr. Ahsan is a Research Engineer at the Georgia Institute of Technology focusing on cardiovascular tissue engineering.
Matheson Hall is located at 32nd and Market Streets.