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Lab Contact Information Lab Web site Address: http://biomechweb.net/biomech/CiBL.htm Lab Phone Number: 215.895.1650 Faculty in Charge Name: Todd C. Doehring Phone: 215.895.1650 Email: tcdoe@drexel.edu Lab Overview CiBL work focuses on developing novel imaging systems, micro-mechanical testing devices, and computational analyses for measuring and modeling the material and structural behavior of collagenous connective tissues and tissue engineered constructs. The primary goal of our research is to understand the complex collagen fiber structure and cell-matrix interactions of connective tissues, and their behavior under physiological loads. These analyses are critical for developing improved microsurgery techniques, for functional tissue engineered constructs, and for directed tissue regeneration. |
| Equipment 1 | |
| Make and Model: | Olympus BX-50 |
| Brief Description of Capability: | Transmission upright microscope, with full computer control in all three axes, and computer controlled high resolution digital imaging system. Normal, polarized and phase contrast imaging capability |
| Location: | 613 Bossone |
| Equipment 2 | |
| Make and Model: | Custom designed micro testing system |
| Brief Description of Capability: | Microstructural Testing System (MSTS) designed to apply multiaxial loads to small tissue specimens. Computer controlled and synchronized with microscope imaging system above. |
| Location: | 613 Bossone |
| Equipment 3 | |
| Make and Model: | Tyan multi-processor analysis computer |
| Brief Description of Capability: |
8 dual processor, (16 cores) computer with 32 Gbytes ram and 1 Terrabyte redundant hard drive. Used for high-throughput image processing and computational analysis of soft tissues—finite element analyses. |
| Location: | 613 Bossone |
| Additional Information (optional) Several custom tissue cutting/slicing systems have been custom made in house for preparing 100-500 micrometer thick sections of soft tissues. These thicker sections are necessary for structural imaging. Custom, unique software and hardware has been developed for creating wide-field ultra-high resolution images using our automated microscope, to be used for ‘virtual histology’. Images as large as 32000x32000 pixels can be created, with fully automatic focus and sub-pixel accurate image tiling. Cost of a commercial system (currently not available) with this capability would be in excess of $250,000. |
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Phone 215.895.2215 | Fax 215.895.4983 | Email biomed@drexel.edu |
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| ©2005 School of Biomedical Engineering, Science & Health Systems. All rights reserved. Terms of Use & Disclaimer | Last Modified: 11/25/2008 |