Peer-Reviewed Articles
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Huang, L., Hu, J., Lang, L., Wang, X., Zhang, P., Jing, X., Wang, X., Chen, X., Lelkes. P.I., MacDiarmid, A.G., and Wei Y. Synthesis and characterization of electroactive and biodegradable ABA block copolymer of polylactide and aniline pentamer   Biomaterials   (2007), 28:1741-1751.  [PDF]

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Botta, G.P., Manley, M., Miller, S., and Lelkes, P.I.    Real-time assessment of three-dimensional cell aggregation in rotating wall vessel bioreactors in vitro.   Nature Protocols,   (2007), 1: 2116-2126..  [PDF]

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Mondrinos, M.J., Koutzaki, S., Lelkes, P.I., and Finck, C.M.    A tissue-engineered model of fetal distal lung tissue   Am J Physiol Lung Cell Mol Physiol.  (2007), 293:L639-650.  [PDF]

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Guo, Y., Li, M., Mylonakis, A., Han, J.G., Macdiarmid, A., Chen, X., Lelkes, P.I., and Wei, Y.   Electroactive Oligoaniline-Containing Self-Assembled Monolayers for Tissue Engineering Applications.    Biomacromolecules  (2007), . 8:3025-3034.  [PDF]

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Moxon KA, Hallman S, Aslani A, Kalkhoran NM, Lelkes PI.   Bioactive properties of nanostructured porous silicon for enhancing electrode to neuron interfaces.    J Biomater Sci Polym Ed. 2007  (2007), ;18(10):  1263-81.  [PDF]

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Vamvakidou, A.P., Mondrinos, M.J., Petushi, S.P., Garcia, F.U., Lelkes, P.I., and Tozeren A. Heterogeneous Breast Tumoroids: An In Vitro Assay for Investigating Cellular Heterogeneity and Drug Delivery   J Biomol Screen.  (2006), 12:13-20.  [PDF]

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Lazarovici, P., Gazit, A., Staniszewska, I., Marcinkiewicz, C., and Lelkes, P.I.Nerve Growth Factor Promotes Angiogenesis in the Quail Chorioallantoic Membrane   Endothelium  (2006), . 13:51-59.  [PDF]

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Dietrich F., and Lelkes, P.I. The three-dimensional microcarrier-based angiogenesis assay and its application for co-culture studies,    Angiogenesis  (2006), 9:111-125.  [PDF]

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Mondrinos, M.J. Dembzynski, R., Lu, L., Byrapogu, V.K.C., Wootton, D.M. Lelkes, P.I, and Zhou, J.Porogen-based Solid Freeform Fabrication of Polycaprolactone-Calcium Phosphate Scaffolds for Tissue Engineering, Biomaterials,    Biomaterials  (2006), 27:4399-4408.  [PDF]

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Manley, P. and Lelkes, P.I. A Novel Real-time System to Monitor Cell Aggregation and Trajectories in Rotating Wall Vessel Bioreactors    , J Biotechnol.  (2006), 125:416-424.  [PDF]

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Li, M., Mondrinos, M.J., Gandhi, M.R., Ko, F.K. Chen, X., and Lelkes, Peter I. Co-electrospun poly(lactide-co-glycolide), gelatin, and elastin blends for tissue engineering scaffolds   . J Biomed Mater Res A  (2006), . 79:963-73.  [PDF]

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Lazarovici, P., Marcinkiewicz, C., and Lelkes, P.I Cross Talk between the Cardiovascular and Nervous Systems: Neurotrophic Effects of Vascular Endothelial Growth Factor (VEGF) and Angiogenic Effects of Nerve Growth Factor (NGF)-Implications in Drug Development   Current Pharmaceutical Design,  (2006), 12:2609-2622.  [PDF]

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Li, Mengyan; Guo, Y.; Wei, Y.; Macdiarmid, A. G.; Lelkes, Peter I.   Electrospinning polyaniline-contained gelatin nanofibers for tissue engineering applications.    Biomaterials. (2006), 27(13), 2705-2715.  Epub 2005 Dec 13.    [Abstract]    [PDF]

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Bidez, Paul R., III; Li, Shuxi; Macdiarmid, Alan G.; Venancio, Everaldo C.; Wei, Yen; Lelkes, Peter I.   Polyaniline, an electroactive polymer, supports adhesion and proliferation of cardiac myoblasts.    Journal of Biomaterials Science, Polymer Edition  (2006),  17(1-2),  199-212.  CODEN: JBSEEA  ISSN:0920-5063.  AN 2006:30357    [Abstract]    [PDF]

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Simons, D. M.; Gardner, E. M.; Lelkes, Peter I.   Dynamic Culture in a Rotating-Wall Vessel Bioreactor Differentially Inhibits Murine T Lymphocyte Activation by Mitogenic Stimuli Upon Return to Static Conditions in a Time-Dependent Manner.    J Appl Physiol., (2005)  Final accepted version: JAP-00887-2005.R1    [Abstract]    [PDF]

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Ritz, B. W.; Lelkes, Peter I.; Gardner, E. M.   Functional recovery of peripheral blood mononuclear cells in modeled microgravity.     FASEB J. (2005), [Epub ahead of print]    [Abstract]    [PDF]

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Uttayarat, P.; Lelkes, Peter I.; Composto, Russell J.   Effect of nano-to micro-scale surface topography on the orientation of endothelial cells.    Materials Research Society Symposium Proceedings  (2005),  845(Nanoscale Materials Science in Biology and Medicine),  157-162.  CODEN: MRSPDH  ISSN:0272-9172.  CAN 143:47978  AN 2005:350711    [Abstract]    [PDF]

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Li, Mengyan; Mondrinos, Mark J.; Gandhi, Milind R.; Ko, Frank K.; Weiss, Anthony S.; Lelkes, Peter I..   Electrospun protein fibers as matrices for tissue engineering.    Biomaterials  (2005),  26(30),  5999-6008.  CODEN: BIMADU  ISSN:0142-9612.  CAN 143:427227  AN 2005:521337    [Abstract]    [PDF]

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Darling, Andrew; Shor, Lauren; Khalil, Saif; Mondrinos, Mark; Lelkes, Peter; Guceri, Selcuk; Sun, Wei.   Multi-material scaffolds for tissue engineering.    Macromolecular Symposia  (2005),  227(Biological and Synthetic Polymer Networks and Gels),  345-355.  CODEN: MSYMEC  ISSN:1022-1360.  CAN 143:392879  AN 2005:969150    [Abstract]    [PDF]

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Wei, Yen; Yin, Houping; Cao, Xiaohua; Ndungu, Patrick; Yang, Guoliang; Bradley, Jean-Claude; Pourrezaei, Kambiz; Lelkes, Peter I.; Tsien, Joe Z.  Nanoelectrodes fabricated from electron beam deposited carbon as potential electrochemical neuronal probes.    Journal of Biomedical Nanotechnology  (2005),  1(3),  336-340.  CODEN: JBNOAB  ISSN:1550-7033.  AN 2005:1182368    [Abstract]    [PDF]

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Dolle, Jean-Pierre; Rezvan, Amir; Allen, Fred D.; Lazarovici, Philip; Lelkes, Peter I..   Nerve growth factor-induced migration of endothelial cells.    Journal of Pharmacology and Experimental Therapeutics  (2005),  315(3),  1220-1227.  CODEN: JPETAB  ISSN:0022-3565.  CAN 144:64710  AN 2005:1326870    [Abstract]    [PDF]

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Mondrinos, Mark J; Koutzaki, S; Jiwanmall, E; Li, Mengyan; Dechadarevian, J P; Lelkes, Peter I.; Finck, C M.   Engineering Three-Dimensional Pulmonary Tissue Constructs.  Tissue Eng. (2005), 12, 1-12. PMID: 16411838    [Abstract]    [PDF]

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Fridman, Gregory; Li, Mengyan; Lelkes, Peter I.; Friedman, Gary; Fridman, Alexander; Gutsol, Alexander F.   Nonthermal plasma bio-active liquid micro and nano-xerography.    IEEE Transactions on Plasma Science  (2005),  33(3),  1061-1065.  CODEN: ITPSBD  ISSN:0093-3813.  AN 2005:607535    [Abstract]    [PDF]

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Huang, Li-Hong; Hu, Jun; Zhuang, Xiu-Li; Ma, Jia; Chen, Xue-Si; Jing, Xia-Bin; Guo, Yi; Li, Meng-Yan; Lelkes, Peter I.; Wei, Yen.   Synthesis and characterization of electro-active and biodegradable block copolymer of aniline pentamer with polylactide.    Gaodeng Xuexiao Huaxue Xuebao  (2005),  26(9),  1771-1773.  CODEN: KTHPDM  ISSN:0251-0790.  CAN 144:74672  AN 2005:1069009    [Abstract]    [PDF]

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Guo, Yi; Wei, Yen; Lelkes, Peter; Ko, Frank K.; Li, Shuxi; Feng, Qiuwei.   Synthesis and characterization of novel electroactive aniline trimer-containing organosilane material.    Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005  (2005),     PMSE-189.  CODEN: 69GQMP  AN 2005:193908    [Abstract]    [PDF]

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Guo, Yi; Wei, Yen; Lelkes, Peter L.; Ko, Frank; Li, Shuxi; Feng, Qiuwei.   Synthesis and characterization of novel electroactive aniline trimer-containing organosilane materials.    PMSE Preprints  (2005),  92  320-321.  CODEN: PPMRA9  ISSN:1550-6703.  CAN 143:78846  AN 2005:183413    [Abstract]    [PDF]

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Uttayarat, Pimpon; Toworfe, George K.; Dietrich, Franziska; Lelkes, Peter I.; Composto, Russell J.   Topographic guidance of endothelial cells on silicone surfaces with micro- to nanogrooves: Orientation of actin filaments and focal adhesions.    Journal of Biomedical Materials Research, Part A  (2005),  75A(3),  668-680.  CODEN: JBMRCH  ISSN:1549-3296.  AN 2005:1258869    [Abstract]    [PDF]

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Martins, Andreia C. P.; Souza, Kleber L. A.; Shio, Marina T.; Mathias, Paulo C. F.; Lelkes, Peter I.; Garcia, Raul M. G.   Adrenal medullary function and expression of catecholamine-synthesizing enzymes in mice with hypothalamic obesity.    Life Sciences  (2004),  74(26),  3211-3222.  CODEN: LIFSAK  ISSN:0024-3205.  CAN 141:21790  AN 2004:320143    [Abstract]    [PDF]

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Brooks, Alan R.; Lelkes, Peter I.; Rubanyi, Gabor M.   Gene expression profiling of vascular endothelial cells exposed to fluid mechanical forces: Relevance for focal susceptibility to atherosclerosis.    Endothelium  (2004),  11(1),  45-57.  CODEN: ENDTE9  ISSN:1062-3329.  CAN 141:51550  AN 2004:367990    [Abstract]    [PDF]

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Rezvan Amir; Allen Fred D; Lelkes Peter I   Steady unidirectional laminar flow inhibits monolayer formation by human and rat microvascular endothelial cells.    Endothelium : journal of endothelial cell research  (2004),  11(1),  11-6.  Journal code: 9412590.  ISSN:1062-3329.  PubMed ID 15203875 AN 2004302714    [Abstract]    [PDF]

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Guo, Yi; Wei, Yen; Lelkes, Peter; Ko, Frank K.; Zhou, YanXiu; Levon, Kalle.   Synthesis and characterization of thiolated aniline oligomers for potential bioconjugation use.    Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, United States, August 22-26, 2004  (2004),     PMSE-320.  CODEN: 69FTZ8  AN 2004:660202    [Abstract]    [PDF]

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Guo, Yi; Wei, Yen; Lelkes, Peter L.; Ko, Frank; Zhou, Yanxiu; Levon, Kalle.   Synthesis and characterization of thiolated aniline oligomers for potential bioconjugation use.    PMSE Preprints  (2004),  91  585-586.  CODEN: PPMRA9  ISSN:1550-6703.  CAN 142:176492  AN 2004:670315    [Abstract]    [PDF]

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Brooks, Alan R.; Lelkes, Peter I.; Rubanyi, Gabor M.   Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow.    Physiological Genomics [online computer file]  (2002),  9(1),  27-41.  CODEN: PHGEFP  ISSN:1094-8341.  CAN 138:104809  AN 2002:439760    [Abstract]    [PDF]

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Silverman, Matthew D.; Tumuluri, Ramagopal J.; Davis, Mishel; Lopez, Gladys; Rosenbaum, James T.; Lelkes, Peter I..   Homocysteine upregulates vascular cell adhesion molecule-1 expression in cultured human aortic endothelial cells and enhances monocyte adhesion.    Arteriosclerosis, Thrombosis, and Vascular Biology  (2002),  22(4),  587-592.  CODEN: ATVBFA  ISSN:1079-5642.  CAN 137:45156  AN 2002:307890    [Abstract]    [PDF]

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Guterman, Elizabeth; Cheng, Shan; Palouian, Kolby; Bidez, Paul; Lelkes, Peter; Wei, Yen.   Peptide-modified electroactive polymers for tissue engineering applications.    Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, 2002  (2002),     POLY-420.  CODEN: 69CZPZ  AN 2002:777443    [Abstract]    [PDF]

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Guterman, Elizabeth; Cheng, Shan; Palouian, Kolby; Bidez, Paul; Lelkes, Peter; Wei, Yen.   Peptide-modified electroactive polymers for tissue engineering applications.    Polymer Preprints (American Chemical Society, Division of Polymer Chemistry)  (2002),  43(2),  766-767.  CODEN: ACPPAY  ISSN:0032-3934.  CAN 138:338609  AN 2002:626640    [Abstract]    [PDF]

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Burnatowska-Hledin, M.; Zeneberg, A.; Roulo, A.; Grobe, J.; Zhao, P.; Lelkes, P. I.; Clare, P.; Barney, C.   Expression of VACM-1 protein in cultured rat adrenal endothelial cells is linked to the cell cycle.    Endothelium  (2001),  8(1),  49-63.  CODEN: ENDTE9  ISSN:1062-3329.  CAN 135:31870  AN 2001:388299    [Abstract]    [PDF]

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Lelkes, Efrat; Unsworth, Brian R.; Lelkes, Peter I..   Reactive oxygen species, apoptosis and altered NGF-induced signaling in PC12 pheochromocytoma cells cultured in elevated glucose: an in vitro cellular model for diabetic neuropathy.    Neurotoxicity Research  (2001),  3(2),  189-203.  CODEN: NURRFI  ISSN:1029-8428.  CAN 136:277260  AN 2001:770712    [Abstract]    [PDF]

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Papadimitriou, E.; Waters, C. R.; Manolopoulos, V. G.; Unsworth, B. R.; Maragoudakis, M. E.; Lelkes, P. I..   Regulation of extracellular matrix remodeling and MMP-2 activation in cultured rat adrenal medullary endothelial cells.    Endothelium  (2001),  8(4),  243-253.  CODEN: ENDTE9  ISSN:1062-3329.  CAN 136:352948  AN 2002:69045    [Abstract]    [PDF]

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Papadimitriou, E.; Waters, C. R.; Manolopoulos, V. G.; Unsworth, B. R.; Maragoudakis, M. E.; Lelkes, P. I..   Regulation of extracellular matrix remodeling and MMP-2 activation in cultured rat adrenal medullary endothelial cells.    Endothelium  (2001),  8(3),  181-194.  CODEN: ENDTE9  ISSN:1062-3329.  CAN 136:352945  AN 2002:59769    [Abstract]    [PDF]

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Nikolaychik V V; Chekanov V S; Hernandez I; Silverman M D; Lelkes P I   Biodesign of a skeletal muscle flap as a model for cardiac assistance.    Artificial organs  (2000),  24(2),  137-47.  Journal code: 7802778.  ISSN:0160-564X.  PubMed ID 10718767 AN 2000184128    [Abstract]    [PDF]

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Manolopoulos, V. G.; Liekens, S.; Koolwijk, P.; Voets, T.; Peters, E.; Droogmans, G.; Lelkes, P. I.; De Clercq, E.; Nilius, B.   Inhibition of angiogenesis by blockers of volume-regulated anion channels.    General Pharmacology  (2000),  34(2),  107-116.  CODEN: GEPHDP  ISSN:0306-3623.  CAN 133:329315  AN 2000:622038    [Abstract]    [PDF]

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Kuehn R; Lelkes P I; Bloechle C; Niendorf A; Izbicki J R   Angiogenesis, angiogenic growth factors, and cell adhesion molecules are upregulated in chronic pancreatic diseases: angiogenesis in chronic pancreatitis and in pancreatic cancer.    Pancreas  (1999),  18(1),  96-103.  Journal code: 8608542.  ISSN:0885-3177.  PubMed ID 9888665 AN 1999103740    [Abstract]    [PDF]

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Abu-Raya, Saleh; Bloch-Shilderman, Eugenia; Lelkes, Peter I.; Trembovler, Victoria; Shohami, Esther; Gutman, Yehuda; Lazarovici, Philip.   Characterization of pardaxin-induced dopamine release from pheochromocytoma cells: role of calcium and eicosanoids.    Journal of Pharmacology and Experimental Therapeutics  (1999),  288(2),  399-406.  CODEN: JPETAB  ISSN:0022-3565.  CAN 130:248126  AN 1999:99709    [Abstract]    [PDF]

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Lelkes, Peter I..   Differential regulation of endothelial cell surface molecules by diverse hemodynamic forces.    Endothelial Cell Research Series  (1999),  6(Mechanical Forces and the Endothelium),  221-248.  CODEN: ECRSFY  ISSN:1384-1270.  CAN 132:91119  AN 1999:653138    [Abstract]    [PDF]

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Lelkes, Peter I.; Editor.   Mechanical Forces and the Endothelium.    (1999),     369 pp.  CAN 131:298065  AN 1999:653412    [Abstract]    [PDF]

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Silverman, M. D.; Waters, C. R.; Hayman, G. T.; Wigboldus, J.; Samet, M. M.; Lelkes, P. I..   Tissue factor activity is increased in human endothelial cells cultured under elevated static pressure.    American Journal of Physiology  (1999),  277(2, Pt. 1),  C233-C242.  CODEN: AJPHAP  ISSN:0002-9513.  CAN 131:270308  AN 1999:562019    [Abstract]    [PDF]

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Unsworth, Brain R.; Hayman, G. Thomas; Carroll, Amie; Lelkes, Peter I..   Tissue-specific alternative mRNA splicing of phenylethanolamine N-methyltransferase (PNMT) during development by intron retention.    International Journal of Developmental Neuroscience  (1999),  17(1),  45-55.  CODEN: IJDND6  ISSN:0736-5748.  CAN 131:126774  AN 1999:245886    [Abstract]    [PDF]

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Kanda, Keiichi; Hayman, G. Thomas; Silverman, Matthew D.; Lelkes, Peter I..   Comparison of ICAM-1 and VCAM-1 expression in various human endothelial cell types and smooth muscle cells.    Endothelium  (1998),  6(1),  33-44.  CODEN: ENDTE9  ISSN:1062-3329.  CAN 129:314831  AN 1998:706249    [Abstract]    [PDF]

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Unsworth, Brian R.; Lelkes, Peter I..   Growing tissues in microgravity.    Nature Medicine (New York)  (1998),  4(8),  901-907.  CODEN: NAMEFI  ISSN:1078-8956.  AN 1998:504058    [Abstract]    [PDF]

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Lelkes, Peter I.; Hahn, Kenneth A.; Karmiol, Soverin; Schmidt, Donald H.   Hypoxia/reoxygenation enhances tube formation of cultured human microvascular endothelial cells: the role of reactive oxygen species.    NATO ASI Series, Series A: Life Sciences  (1998),  298(Angiogenesis),  321-336.  CODEN: NALSDJ  ISSN:0258-1213.  CAN 129:314333  AN 1998:563449    [Abstract]    [PDF]

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Henry M K; Unsworth B R; Sychev V; Guryeva T S; Dadasheva O A; Piert S J; Lagel K E; Dubrovin L C; Jahns G C; Boda K; Sabo V; Samet M M; Lelkes P I   Launch conditions might affect the formation of blood vessels in the quail chorioallantoic membrane.    Folia veterinaria  (1998),  42 Suppl S25-31.  Journal code: 0355211.  ISSN:0015-5748.  PubMed ID 11543304 AN 2001661887    [Abstract]    [PDF]

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Lelkes P I; Hahn K L; Sukovich D A; Karmiol S; Schmidt D H   On the possible role of reactive oxygen species in angiogenesis.    Advances in experimental medicine and biology  (1998),  454 295-310.  Journal code: 0121103.  ISSN:0065-2598.  PubMed ID 9889904 AN 1999106578    [Abstract]    [PDF]

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Lelkes, Peter I.; Calvan, Daniel L.; Hayman, G. Thomas; Goodwin, Thomas J.; Chatman, Dawn Y.; Cherian, Sunu; Garcia, Raul M. G.; Unsworth, Brian R.   Simulated microgravity conditions enhance differentiation of cultured PC12 cells towards the neuroendocrine phenotype.    In Vitro Cellular & Developmental Biology: Animal  (1998),  34(4),  316-325.  CODEN: IVCAED  ISSN:1071-2690.  CAN 129:79639  AN 1998:284158    [Abstract]    [PDF]

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Jiang, Hao; Movsesyan, Vilen; Fink, Donald W., Jr.; Fasler, Monika; Whalin, Michael; Katagiri, Yasuhiro; Monshipouri, Mariam; Dickens, Geneva; Lelkes, Peter I.; Guroff, Gordon; Lazarovici, Philip.   Expression of human p140trk receptors in p140trk-deficient, PC12/endothelial cells results in nerve growth factor-induced signal transduction and DNA synthesis.    Journal of Cellular Biochemistry  (1997),  66(2),  229-244.  CODEN: JCEBD5  ISSN:0730-2312.  CAN 127:131530  AN 1997:452058    [Abstract]    [PDF]

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Lelkes, Peter I.; Ramos, Esther; Nikolaychik, Victor V.; Wankowski, Dawn M.; Unsworth, Brian R.; Goodwin, Thomas J.   GTSF-2: a new, versatile cell culture medium for diverse normal and transformed mammalian cells.    In Vitro Cellular & Developmental Biology: Animal  (1997),  33(5),  344-351.  CODEN: IVCAED  ISSN:1071-2690.  CAN 127:132994  AN 1997:438754    [Abstract]    [PDF]

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Manolopoulos, Vangelis G.; Fenton, John W., II; Lelkes, Peter I..   The thrombin receptor in adrenal medullary microvascular endothelial cells is negatively coupled to adenylyl cyclase through a Gi protein.    Biochimica et Biophysica Acta, Molecular Cell Research  (1997),  1356(3),  321-332.  CODEN: BBAMCO  ISSN:0167-4889.  CAN 126:341584  AN 1997:273223    [Abstract]    [PDF]

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Papadimitriou, Evangelia; Manolopoulos, Vangelis G.; Hayman, G. Thomas; Maragoudakis, Michael E.; Unsworth, Brian R.; Fenton, John W., II; Lelkes, Peter I..   Thrombin modulates vectorial secretion of extracellular matrix proteins in cultured endothelial cells.    American Journal of Physiology  (1997),  272(4, Pt. 1),  C1112-C1122.  CODEN: AJPHAP  ISSN:0002-9513.  CAN 127:48255  AN 1997:326904    [Abstract]    [PDF]

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Nikolaychik, V. V.; Samet, M. M.; Lelkes, P. I..   A new method for continual quantitation of viable cells on endothelialized polyurethanes.    Journal of Biomaterials Science, Polymer Edition  (1996),  7(10),  881-891.  CODEN: JBSEEA  ISSN:0920-5063.  CAN 125:151019  AN 1996:464147    [Abstract]    [PDF]

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Chekanov, Valeri S.; Tchekanov, Guennady V.; Rieder, Michelle A.; Eisenstein, Rueben; Wankowski, Dawn M.; Schmidt, Donald H.; Nikolaychik, Victor V.; Lelkes, Peter I..   Biologic glue increases capillary ingrowth after cardiomyoplasty in an ischemic cardiomyopathy model.    ASAIO Journal  (1996),  42(5),  M480-M487.  CODEN: AJOUET  ISSN:1058-2916.  CAN 127:314605  AN 1997:673917    [Abstract]    [PDF]

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Nikolaychik V V; Wankowski D M; Samet M M; Lelkes P I   In vitro testing of endothelial cell monolayers under dynamic conditions inside a beating ventricular prosthesis.    ASAIO journal (American Society for Artificial Internal Organs : 1992)  (1996),  42(5),  M487-94.  Journal code: 9204109.  ISSN:1058-2916.  PubMed ID 8944928 AN 97100367    [Abstract]    [PDF]

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Lelkes, Peter I.; Manolopoulos, Vangelis G.; Silverman, Matthew; Zhang, Shaosong; Karmiol, Soverin; Unsworth, Brian R.   On the possible role of endothelial cell heterogeneity in angiogenesis.    NATO ASI Series, Series A: Life Sciences  (1996),  285(Molecular, Cellular, and Clinical Aspects of Angiogenesis),  1-17.  CODEN: NALSDJ  ISSN:0258-1213.  CAN 125:297563  AN 1996:640880    [Abstract]    [PDF]

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Rasouly, David; Shavit, Davidit; Zuniga, Ramiro; Elejalde, Rafael B.; Unsworth, Brian R.; Yayaon, Avner; Lazarovici, Philip; Lelkes, Peter I..   Staurosporine induces neurite outgrowth in neuronal hybrids (PC12EN) lacking NGF receptors.    Journal of Cellular Biochemistry  (1996),  62(3),  356-371.  CODEN: JCEBD5  ISSN:0730-2312.  CAN 125:218086  AN 1996:552688    [Abstract]    [PDF]

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Garcia, Raul Marcel Gonzalez; Atwater, Illani; Lelkes, Peter; Mathias, Paulo Cezar de Freitas.   The inhibition of K+-secretory response by caffeine in bovine chromaffin cells is time dependent.    Research Communications in Alcohol and Substances of Abuse  (1996),  17(1&2),  15-21.  CODEN: RCAAE3  ISSN:1080-8388.  CAN 126:14674  AN 1996:735994    [Abstract]    [PDF]

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Shilderman-Bloch, E.; Abu-Raya, S.; Rasouly, D.; Furman, O.; Trumbovler, V.; Shavit, D.; Lelkes, P. I.; Shohami, E.; Gutman, Y.; Lazarovici, P.   The role of calcium, protein kinase C, pertussis toxin substrates and eicosanoids on pardaxin induced dopamine release from PC12 pheochromocytoma cells.    Biochemical Aspects of Marine Pharmacology  (1996),     158-174.  CODEN: 63EAAF  CAN 125:135200  AN 1996:490705    [Abstract]    [PDF]

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Silverman, M. D.; Manolopoulos, V. G.; Unsworth, B. R.; Lelkes, P. I..   Tissue factor expression is differentially modulated by cyclic mechanical strain in various human endothelial cells.    Blood Coagulation & Fibrinolysis  (1996),  7(3),  281-288.  CODEN: BLFIE7  ISSN:0957-5235.  CAN 125:82710  AN 1996:404005    [Abstract]    [PDF]

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Manolopoulos, Vangelis G.; Liu, Jiandong; Unsworth, Brian R.; Lelkes, Peter I..   Adenylyl cyclase isoforms are differentially expressed in primary cultures of endothelial cells and whole tissue homogenates from various rat tissues.    Biochemical and Biophysical Research Communications  (1995),  208(1),  323-31.  CODEN: BBRCA9  ISSN:0006-291X.  CAN 122:183917  AN 1995:415817    [Abstract]    [PDF]

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Samad, F.; Bergtrom, G.; Lelkes, P. I.; Rajappa, V.; Amrani, D. L.   Differential cytokine regulation of PAI-1 gene expression between human umbilical and subcutaneous fat-derived microvascular endothelial cells.    Endothelium  (1995),  3(3),  243-52.  CODEN: ENDTE9  ISSN:1062-3329.  CAN 124:199996  AN 1996:116709    [Abstract]    [PDF]

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Thomas G A; Lelkes P I; Isoda S; Chick D; Lu H; Hammond R L; Nakajima H; Nakajima H; Walters H L 3rd; Stephenson L W   Endothelial cell-lined skeletal muscle ventricles in circulation.    Journal of thoracic and cardiovascular surgery  (1995),  109(1),  66-73.  Journal code: 0376343.  ISSN:0022-5223.  PubMed ID 7815809 AN 95115409    [Abstract]    [PDF]

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Thomas G A; Lelkes P I; Chick D M; Lu H; Kowal T A; Hammond R L; Nakajima H; Nakajima H; Spanta A D; Stephenson L W   Endothelial lined skeletal muscle ventricles: open and percutaneous seeding techniques.    Journal of cardiac surgery  (1995),  10(3),  245-56.  Journal code: 8908809.  ISSN:0886-0440.  PubMed ID 7626875 AN 95352950    [Abstract]    [PDF]

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Manolopoulos, Vangelis G.; Samet, Mark M.; Lelkes, Peter I..   Regulation of the adenylyl cyclase signaling system in various types of cultured endothelial cells.    Journal of Cellular Biochemistry  (1995),  57(4),  590-8.  CODEN: JCEBD5  ISSN:0730-2312.  CAN 122:287622  AN 1995:512896    [Abstract]    [PDF]

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Thomas G A; Lelkes P I; Chick D M; Isoda S; Lu H; Nakajima H; Hammond R L; Nakajima H; Walters H L 3rd; Stephenson L W   Skeletal muscle ventricles seeded with autogenous endothelium.    ASAIO journal (American Society for Artificial Internal Organs : 1992)  (1995),  41(2),  204-11.  Journal code: 9204109.  ISSN:1058-2916.  PubMed ID 7640429 AN 95367719    [Abstract]    [PDF]

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Nikolaychik V V; Samet M M; Lelkes P I   A new, cryoprecipitate based coating for improved endothelial cell attachment and growth on medical grade artificial surfaces.    ASAIO journal (American Society for Artificial Internal Organs : 1992)  (1994),  40(3),  M846-52.  Journal code: 9204109.  ISSN:1058-2916.  PubMed ID 8555633 AN 96145477    [Abstract]    [PDF]

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Lelkes P I   Cytotoxicity of carbobenzoxy-protected amino acids.    In vitro cellular & developmental biology. Animal  (1994),  30A(2),  75-6.  Journal code: 9418515.  ISSN:1071-2690.  PubMed ID 8012657 AN 94282395    [Abstract]    [PDF]

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Lelkes P I; Gao H; Edgerton J R; Christensen C W   Endothelial cell seeding of latissimus dorsi muscle pouches.    Journal of surgical research  (1994),  57(4),  460-9.  Journal code: 0376340.  ISSN:0022-4804.  PubMed ID 7934023 AN 95019635    [Abstract]    [PDF]

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Wankowski D M; Samet M M; Nikolaychik V V; Lelkes P I   Endothelial cell seeding with rotation of a ventricular blood sac.    ASAIO journal (American Society for Artificial Internal Organs : 1992)  (1994),  40(3),  M319-24.  Journal code: 9204109.  ISSN:1058-2916.  PubMed ID 8555532 AN 96145376    [Abstract]    [PDF]

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Haralabopoulos, George C.; Grant, Derrick S.; Kleinman, Hynda K.; Lelkes, Peter I.; Papaioannou, S. P.; Maragoudakis, Michael E.   Inhibitors of basement membrane collagen synthesis prevent endothelial cell alignment in matrigel in vitro and angiogenesis in vivo.    Laboratory Investigation  (1994),  71(4),  575-82.  CODEN: LAINAW  ISSN:0023-6837.  CAN 122:23466  AN 1995:223382    [Abstract]    [PDF]

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Lelkes, Peter I.; Ramos, Esther M.; Chick, Dawn M.; Liu, Jiandong; Unsworth, Brian R.   Microgravity decreases tyrosine hydroxylase expression in rat adrenals.    FASEB Journal  (1994),  8(14),  1177-82.  CODEN: FAJOEC  ISSN:0892-6638.  CAN 122:1602  AN 1995:224645    [Abstract]    [PDF]

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Samet M M; Lelkes P I   Pulsatile flow and endothelial cell morphology in a cell culture chamber model of an artificial cardiac ventricle.    Journal of biomechanical engineering  (1994),  116(3),  369-71.  Journal code: 7909584.  ISSN:0148-0731.  PubMed ID 7799641 AN 95097601    [Abstract]    [PDF]

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Lin, Horng Ban; Sun, Wen; Mosher, Deane F.; Garcia-Echeverria, Carlos; Schaufelberger, Kenneth; Lelkes, Peter I.; Cooper, Stuart L.   Synthesis, surface, and cell-adhesion properties of polyurethanes containing covalently grafted RGD-peptides.    Journal of Biomedical Materials Research  (1994),  28(3),  329-42.  CODEN: JBMRBG  ISSN:0021-9304.  CAN 120:253291  AN 1994:253291    [Abstract]    [PDF]

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Manolopoulos, Vangelis G.; Lelkes, Peter I..   Cyclic strain and forskolin differentially induce cAMP production in phenotypically diverse endothelial cells.    Biochemical and Biophysical Research Communications  (1993),  191(3),  1379-85.  CODEN: BBRCA9  ISSN:0006-291X.  CAN 118:252244  AN 1993:252244    [Abstract]    [PDF]

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Wilke, Russell A.; Riley, Danny A.; Lelkes, Peter I.; Hillard, Cecilia J.   Decreased catecholamine secretion from the adrenal medullae of chronically diabetic BB-Wistar rats.    Diabetes  (1993),  42(6),  862-8.  CODEN: DIAEAZ  ISSN:0012-1797.  CAN 119:114751  AN 1993:514751    [Abstract]    [PDF]

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Samet M M; Lelkes P I   Flow patterns and endothelial cell morphology in a simplified model of an artificial ventricle.    Cell biophysics  (1993),  23(1-3),  139-63.  Journal code: 8002185.  ISSN:0163-4992.  PubMed ID 7895248 AN 95202694    [Abstract]    [PDF]

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Papadimitriou E; Lelkes P I   Measurement of cell numbers in microtiter culture plates using the fluorescent dye Hoechst 33258.    Journal of immunological methods  (1993),  162(1),  41-5.  Journal code: 1305440.  ISSN:0022-1759.  PubMed ID 7685366 AN 93286432    [Abstract]    [PDF]

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Samet M M; Chick D M; Christensen C W; Lelkes P I   Morphology and integrity of endothelial cell monolayers inside a ventricle shaped perfusion chamber.    ASAIO journal (American Society for Artificial Internal Organs : 1992)  (1993),  39(3),  M403-9.  Journal code: 9204109.  ISSN:1058-2916.  PubMed ID 8268567 AN 94093113    [Abstract]    [PDF]

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Maragoudakis, Michael E.; Gullino, Pietro; Lelkes, Peter I.; Editors.   Angiogenesis in Health and Disease.  (Proceedings of a NATO Advanced Study Institute on Angiogenesis in Health and Diseases, held June 16-27, 1991, in Porto Hydra, Greece.)  [In:  NATO ASI Ser., Ser. A:  Life Sciences, 1992; 227].    (1992),     402 pp.  CAN 118:78654  AN 1993:78654    [Abstract]    [PDF]

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Christensen C W; Samet M M; Chick D M; Lelkes P I   Experimental studies of pulsatile flow and endothelial cell adaptation in ventricle shaped cell culture chambers.    ASAIO journal (American Society for Artificial Internal Organs : 1992)  (1992),  38(3),  M501-6.  Journal code: 9204109.  ISSN:1058-2916.  PubMed ID 1457911 AN 93091358    [Abstract]    [PDF]

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Lazarovici, Philip; Lelkes, Peter I..   Pardaxin induces exocytosis in bovine adrenal medullary chromaffin cells independent of calcium.    Journal of Pharmacology and Experimental Therapeutics  (1992),  263(3),  1317-26.  CODEN: JPETAB  ISSN:0022-3565.  CAN 118:74142  AN 1993:74142    [Abstract]    [PDF]

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Lelkes P I; Samet M M   Endothelialization of the luminal sac in artificial cardiac prostheses: a challenge for both biologists and engineers.    Journal of biomechanical engineering  (1991),  113(2),  132-42.  Journal code: 7909584.  ISSN:0148-0731.  PubMed ID 1875687 AN 91342204    [Abstract]    [PDF]

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Grant D S; Lelkes P I; Fukuda K; Kleinman H K   Intracellular mechanisms involved in basement membrane induced blood vessel differentiation in vitro.    In vitro cellular & developmental biology : journal of the Tissue Culture Association  (1991),  27A(4),  327-36.  Journal code: 8506951.  ISSN:0883-8364.  PubMed ID 1856158 AN 91310556    [Abstract]    [PDF]

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Yuli, Itzhak; Lelkes, Peter I..   Neutral endopeptidase activity in the interaction of N-formyl-L-methionyl-L-leucyl-L-phenylalanine with human polymorphonuclear leukocytes.    European Journal of Biochemistry  (1991),  201(2),  421-30.  CODEN: EJBCAI  ISSN:0014-2956.  CAN 115:205857  AN 1991:605857    [Abstract]    [PDF]

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Lelkes P I   New aspects of endothelial cell biology.    Journal of cellular biochemistry  (1991),  45(3),  242-4.  Journal code: 8205768.  ISSN:0730-2312.  PubMed ID 2066372 AN 91294241    [Abstract]    [PDF]

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Lelkes P I; Samet M M   Pulsatile flow and EC morphology in a VAD-like chamber.    ASAIO transactions / American Society for Artificial Internal Organs  (1991),  37(3),  M315-6.  Journal code: 8611947.  ISSN:0889-7190.  PubMed ID 1751167 AN 92088676    [Abstract]    [PDF]

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Brandi M L; Ornberg R L; Sakaguchi K; Curcio F; Fattorossi A; Lelkes P I; Matsui T; Zimering M; Aurbach G D   Establishment and characterization of a clonal line of parathyroid endothelial cells.    FASEB journal : official publication of the Federation of American Societies for Experimental Biology  (1990),  4(13),  3152-8.  Journal code: 8804484.  ISSN:0892-6638.  PubMed ID 1698682 AN 91006990    [Abstract]    [PDF]

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Lazarovici, P.; Primor, N.; Gennaro, J.; Fox, J.; Shai, Y.; Lelkes, P. I.; Caratsch, C. G.; Raghunathan, G.; Guy, H. R.; et al.   Origin, chemistry, and mechanisms of action of a repellent, presynaptic excitatory, ionophore polypeptide.    ACS Symposium Series  (1990),  418(Mar. Toxins),  347-64.  CODEN: ACSMC8  ISSN:0097-6156.  CAN 112:153106  AN 1990:153106    [Abstract]    [PDF]

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Mizrachi, Yaffa; Naranjo, Jose R.; Levi, Ben Zion; Pollard, Harvey B.; Lelkes, Peter I..   PC12 cells differentiate into chromaffin cell-like phenotype in coculture with adrenal medullary endothelial cells.    Proceedings of the National Academy of Sciences of the United States of America  (1990),  87(16),  6161-5.  CODEN: PNASA6  ISSN:0027-8424.  CAN 113:129905  AN 1990:529905    [Abstract]    [PDF]

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Lazarovici, Philip; Fujita, Ko; Contreras, Margarita L.; DiOrio, James P.; Lelkes, Peter I..   Affinity purified tetanus toxin binds to isolated chromaffin granules and inhibits catecholamine release in digitonin-permeabilized chromaffin cells.    FEBS Letters  (1989),  253(1-2),  121-8.  CODEN: FEBLAL  ISSN:0014-5793.  CAN 111:148515  AN 1989:548515    [Abstract]    [PDF]

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Criscuolo, Gregory R.; Lelkes, Peter I.; Rotrosen, Daniel; Oldfield, Edward H.   Cytosolic calcium changes in endothelial cells induced by a protein product of human gliomas containing vascular permeability factor activity.    Journal of Neurosurgery  (1989),  71(6),  884-91.  CODEN: JONSAC  ISSN:0022-3085.  CAN 112:74707  AN 1990:74707    [Abstract]    [PDF]

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Lazarovici, P.; Levi, B. Z.; Lelkes, P. I.; Koizumi, S.; Fujita, K.; Matsuda, Y.; Ozato, K.; Guroff, Gordon.   K-252a inhibits the increase in c-fos transcription and the increase in intracellular calcium produced by nerve growth factor in PC12 cells.    Journal of Neuroscience Research  (1989),  23(1),  1-8.  CODEN: JNREDK  ISSN:0360-4012.  CAN 111:91152  AN 1989:491152    [Abstract]    [PDF]

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Mizrachi Y; Lelkes P I; Ornberg R L; Goping G; Pollard H B   Specific adhesion between pheochromocytoma (PC12) cells and adrenal medullary endothelial cells in co-culture.    Cell and tissue research  (1989),  256(2),  365-72.  Journal code: 0417625.  ISSN:0302-766X.  PubMed ID 2731223 AN 89275180    [Abstract]    [PDF]

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Fink, Don; Contreras, Margarita L.; Lelkes, Peter I.; Lazarovici, Philip.   Staphylococcus aureus  -toxin activates phospholipases and induces a calcium influx in PC12 cells.    Cellular Signalling  (1989),  1(4),  387-93.  CODEN: CESIEY  ISSN:0898-6568.  CAN 112:2380  AN 1990:2380    [Abstract]    [PDF]

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Lelkes, Peter I.; Lazarovici, Philip.   Pardaxin induces aggregation but not fusion of phosphatidylserine vesicles.    FEBS Letters  (1988),  230(1-2),  131-6.  CODEN: FEBLAL  ISSN:0014-5793.  CAN 109:34162  AN 1988:434162    [Abstract]    [PDF]

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Lelkes, Peter I.; Pollard, Harvey B.   Oligopeptide inhibitors of metalloendoprotease activity inhibit catecholamine secretion from bovine adrenal chromaffin cells by modulating intracellular calcium homeostasis.    Journal of Biological Chemistry  (1987),  262(32),  15496-505.  CODEN: JBCHA3  ISSN:0021-9258.  CAN 107:191513  AN 1987:591513    [Abstract]    [PDF]

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Megnin, Frederique; Faustino, Patrick J.; Lyon, Robbe C.; Lelkes, Peter I.; Cohen, Jack S.   Studies on the mechanism of selective retention of porphyrins and metalloporphyrins by cancer cells.    Biochimica et Biophysica Acta, Molecular Cell Research  (1987),  929(2),  173-81.  CODEN: BBAMCO  ISSN:0167-4889.  CAN 107:92787  AN 1987:492787    [Abstract]    [PDF]

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Stutzin, A.; Cabantchik, Z. I.; Lelkes, P. I.; Pollard, H. B.   Synexin-mediated fusion of bovine chromaffin granule ghosts.  Effect of pH.    Biochimica et Biophysica Acta, Biomembranes  (1987),  905(1),  205-12.  CODEN: BBBMBS  ISSN:0005-2736.  CAN 108:90119  AN 1988:90119    [Abstract]    [PDF]

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Duling B R; Hogan R D; Langille B L; Lelkes P; Segal S S; Vatner S F; Weigelt H; Young M A   Vasomotor control: functional hyperemia and beyond.    Federation proceedings  (1987),  46(2),  251-63.  Journal code: 0372771.  ISSN:0014-9446.  PubMed ID 3542588 AN 87106055    [Abstract]    [PDF]

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Somjen, Giora J.; Marikovsky, Yehuda; Lelkes, Peter; Gilat, Tuvia.   Cholesterol-phospholipid vesicles in human bile:  an ultrastructural study.    Biochimica et Biophysica Acta, Lipids and Lipid Metabolism  (1986),  879(1),  14-21.  CODEN: BBLLA6  ISSN:0005-2760.  CAN 105:206938  AN 1986:606938    [Abstract]    [PDF]

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Friedman, Jonathan E.; Lelkes, Peter I.; Rosenheck, Kurt; Oplatka, Avraham.   Control of stimulus-secretion coupling in adrenal medullary chromaffin cells by microfilament-specific macromolecules.    Journal of Biological Chemistry  (1986),  261(13),  5745-50.  CODEN: JBCHA3  ISSN:0021-9258.  CAN 104:219727  AN 1986:219727    [Abstract]    [PDF]

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Lelkes, Peter I.; Friedman, Jonathan E.; Rosenheck, Kurt; Oplatka, Avraham.   Destabilization of actin filaments as a requirement for the secretion of catecholamines from permeabilized chromaffin cells.    FEBS Letters  (1986),  208(2),  357-63.  CODEN: FEBLAL  ISSN:0014-5793.  CAN 106:28179  AN 1987:28179    [Abstract]    [PDF]

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Lelkes, Peter I.; Friedman, Jonathan E.; Rosenheck, Kurt.   Direct fluorometric assay of catecholamine secretion from isolated bovine adrenal chromaffin cells.    Journal of Neuroscience Methods  (1985),  13(3-4),  249-55.  CODEN: JNMEDT  ISSN:0165-0270.  CAN 103:81835  AN 1985:481835    [Abstract]    [PDF]

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Braun, Gur; Lelkes, Peter I.; Nir, Shlomo.   Effect of cholesterol on calcium-induced aggregation and fusion of sonicated phosphatidylserine/cholesterol vesicles.    Biochimica et Biophysica Acta, Biomembranes  (1985),  812(3),  688-94.  CODEN: BBBMBS  ISSN:0005-2736.  CAN 102:91715  AN 1985:91715    [Abstract]    [PDF]

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Pollard H B; Ornberg R; Levine M; Kelner K; Morita K; Levine R; Forsberg E; Brocklehurst K W; Duong L; Lelkes P I; +   Hormone secretion by exocytosis with emphasis on information from the chromaffin cell system.    Vitamins and hormones  (1985),  42 109-96.  Journal code: 0413601.  ISSN:0083-6729.  PubMed ID 3913120 AN 86153633    [Abstract]    [PDF]

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Lelkes, Peter I.; Friedman, Jonathan E.   Interaction of French-pressed liposomes with isolated bovine adrenal chromaffin cells.  Characterization of the cell-liposome interactions.    Journal of Biological Chemistry  (1985),  260(3),  1796-803.  CODEN: JBCHA3  ISSN:0021-9258.  CAN 102:93752  AN 1985:93752    [Abstract]    [PDF]

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Friedman, J. E.; Lelkes, P. I.; Lavie, E.; Rosenheck, K.; Schneeweiss, F.; Schneider, A. S.   Membrane potential and catecholamine secretion by bovine adrenal chromaffin cells:  use of tetraphenylphosphonium distribution and carbocyanine dye fluorescence.    Journal of Neurochemistry  (1985),  44(5),  1391-402.  CODEN: JONRA9  ISSN:0022-3042.  CAN 102:215890  AN 1985:215890    [Abstract]    [PDF]

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Pollard H B; Ornberg R; Levine M; Brocklehurst K; Forsberg E; Lelkes P I; Morita K   Regulation of secretion from adrenal chromaffin cells.    Physiologist  (1985),  28(4),  247-54.  Journal code: 0401143.  ISSN:0031-9376.  PubMed ID 2931732 AN 86017204    [Abstract]    [PDF]

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Bental, Michal; Lelkes, Peter I.; Scholma, Janny; Hoekstra, Dick; Wilschut, Jan.   Calcium-independent, protein-mediated fusion of chromaffin granule ghosts with liposomes.    Biochimica et Biophysica Acta, Biomembranes  (1984),  774(2),  296-300.  CODEN: BBBMBS  ISSN:0005-2736.  CAN 101:86049  AN 1984:486049    [Abstract]    [PDF]

More than 300 published abstracts of presentations at local, national, and international conferences